Professor Andrew Godkin, Cardiff University – Programme Grant
Project Title: Exploring the immunogenicity of colorectal cancer and its implications for immunotherapy
Duration: 60 months
Cancer Immunotherapy, which seeks to harness the power of a patient’s own immune system for the eradication of cancer, has rapidly emerged as an exciting new treatment for a number of different cancer types. This programme of research will build upon previous ground-breaking work in the area by Professor Godkin and his team. Specifically, the focus will be the identification of novel tumour targets to inform the design and development of new cancer vaccines for improved immune targeting of bowel cancer, Wales’s second leading cause of cancer death. The work will seek to discover molecular fingerprints in the immune system of bowel patients for the development of diagnostic tests that can aid early bowel cancer detection and improve the accuracy of prognosis.
Professor Richard Neal , Bangor University – Programme Grant
Project Title: ‘WICKED’ (Wales Interventions and Cancer Knowledge about Early Diagnosis): The development and evaluation of primary care interventions to expedite the diagnosis of symptomatic cancer in Wales
Duration: 60 months
Wales has poorer outcomes for cancer survival than other countries, with late cancer diagnosis thought to be a significant factor. Early cancer diagnosis is critical as it results in the detection of cancers at a stage when they easier to treat and manage, leading to better survival. Late cancer diagnosis is complex but amongst the contributing factors is the length of the ‘primary care interval’ – the time taken between presentation, and GP’s investigation and referral. This programme of research aims to develop and evaluate educational intervention tools within the primary care setting, aimed at achieving earlier referral and diagnosis of symptomatic cancer in Wales, thereby helping to improve survival.